Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-1-27
pubmed:abstractText
In utero exposure to betamethasone on days 26 and 27 of gestation resulted in a significant increase in lung lavage phospholipid after 24 h of air breathing in rabbit pups delivered at 29 days of gestation. At 6 h of age, the proportion of type II epithelial cells in betamethasone-exposed newborns was nearly twice the saline-exposed control value. Phospholipid composition and pressure:volume analysis of compliance were both unaffected by betamethasone treatment. The betamethasone-associated increase in airway phospholipid content was observed only in female pups. These data support the conclusion that antenatal betamethasone treatment elicits an increase in airway phospholipid which is dependent on breathing and confined to the female newborn.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0379-8305
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
388-403
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Postnatal increase in airway surfactant in the premature rabbit exposed in utero to betamethasone.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.