Linked Life Data

6683749

Source:http://linkedlifedata.com/resource/pubmed/id/6683749

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-9-23
pubmed:abstractText
Autoantibodies to neurofilaments were found by the immunofluorescence technique in serum of patients with postencephalitic (von Economo's) and idiopathic Parkinson's disease in the same proportion as in age-matched neurological and non-neurological controls. In addition, similar neurofibrillary staining was detected in age groups of 29 years and younger, but rarely in the first year of life. Persons over 70, with or without disease, showed a prevalence of antibodies significantly higher than in persons under 70. Serum from 1 case of Alzheimer's disease out of 4 tested, was positive for neurofilament antibodies; serum from the only case of Creutzfeldt-Jakob disease tested was negative. A total of 298 serum specimens, each from a different person, was tested. The use of cryostat-frozen longitudinal sections of normal rat spinal cord as a substrate has been confirmed to be an effective, reproducible and simple procedure for the detection of antineurofilament antibodies in human sera by indirect immunofluorescence.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-510X
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Antineurofilament antibodies in postencephalitic and idiopathic Parkinson's disease.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.