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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1983-7-15
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pubmed:abstractText |
Chronic treatment of rats by subcutaneously implanted A-depot capsules lead through a ca. 12 h hyperglycaemia to hypoglycaemia at 18 h p.o. SDH and G-6-Phase activities in the liver were compared during hyper- and hypoglycaemia using both histochemical and biochemical methods. The results show high triglyceride-contents, lack of glycogen and high G-6-Pase activities in the livers of animals during both hyper- and hypoglycaemia. Striking differences were found concerning SDH-activities: While biochemical measurements show enhanced activities during hyperglycaemia, hypoglycaemic values remain in the "normal" range. Nevertheless histochemical investigations show an amazing re-distribution of SDH-activities from the periportal areas towards the lobule centre. Therefore we think, that biochemical and histochemical methods should be combined to unveil such pseudonormalities. Further, this re-distribution shows the ability of the liver to cope with damage by shifting important processes away from fat-infiltrated areas.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0232-1513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-20
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6682799-Animals,
pubmed-meshheading:6682799-Epinephrine,
pubmed-meshheading:6682799-Female,
pubmed-meshheading:6682799-Glucosephosphate Dehydrogenase,
pubmed-meshheading:6682799-Hyperglycemia,
pubmed-meshheading:6682799-Hypoglycemia,
pubmed-meshheading:6682799-Liver,
pubmed-meshheading:6682799-Male,
pubmed-meshheading:6682799-Rats,
pubmed-meshheading:6682799-Rats, Inbred Strains,
pubmed-meshheading:6682799-Succinate Dehydrogenase
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pubmed:year |
1983
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pubmed:articleTitle |
Comparison of adrenaline-induced hyper- and hypoglycaemia by histological and biochemical investigation.
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pubmed:publicationType |
Journal Article
|