Linked Life Data

6682740

Source:http://linkedlifedata.com/resource/pubmed/id/6682740

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-7-15
pubmed:abstractText
Sixty-two calcium balance and 47Ca-turnover studies were performed in 51 individuals to evaluate the accuracy and the sensitivity of the methods. The data were analysed according to a modification of the expanding calcium pool model using an improved Bauer-Carlsson-Lindquist (BCL) formulation and an iterative computer procedure. A 7-day whole body retention curve (R1) combined with a retention curve constructed from excretion data alone (R2) was used to estimate dermal calcium loss (d) and to demonstrate the significance of individual corrections for delay in faecal excretion (faecal lag time = delta t). The mean d was 1.58 mmol Ca/day. The introduction of delta t improved the goodness of fit of the data to the model. delta t based on 47Ca-kinetics was superior to a fixed delta t of zero (P less than 0.01) or 2 days (P less than 0.05). The model derived renal calcium excretion rate was highly correlated (r = 0.98, P less than 0.001) to the chemical measured excretion rate. A similar highly significant correlation [RS = 0.78 (Spearman), P less than 0.001] was found between the model derived delta t and the carmine red delta t. These results indicate a high accuracy of the model. The directly measured parameters showed an excellent reproducibility with a coefficient of variation (CV) less than 4%. The reproducibility of the derived parameters was acceptable (CV = 10-20%) except for the balance (CV = 72%).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0144-5979
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-204
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Calcium metabolism evaluated by 47calcium-kinetics: a physiological model with correction for faecal lag time and estimation of dermal calcium loss.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't