pubmed-article:6682404 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:6682404 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:6682404 | lifeskim:mentions | umls-concept:C0441635 | lld:lifeskim |
pubmed-article:6682404 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
pubmed-article:6682404 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:6682404 | pubmed:dateCreated | 1983-6-17 | lld:pubmed |
pubmed-article:6682404 | pubmed:abstractText | Early replication of prometaphasic human sex chromosomes was studied with the bromodeoxyuridine (BrdU)-replication technique. The studies reveal that two distal segments of Xp, including bands Xp 22.13 and Xp 22.3, replicate early in S-phase and therefore may not be subject to random inactivation. Furthermore, the replication of these distal segments of Xp occurs synchronously with those of the short arm of the Y chromosome including bands Yp 11.2 and Yp 11.32. These segments of Xp and Yp correspond well to the pairing segment of the X and Y chromosomes where a synaptonemal complex forms at early pachytene of human spermatogenesis. The homologous early replication of Yp and the distal portion of Xp may be interpreted as a remnant left untouched by the differentiation of heteromorphic sex chromosomes from originally homomorphic autosomes. A third early replicating segment is situated on the long arm of the X chromosome and corresponds to band Xq 13.1. This segment may be correlated with the X-inactivation center postulated by Therman et al. (1979). | lld:pubmed |
pubmed-article:6682404 | pubmed:language | eng | lld:pubmed |
pubmed-article:6682404 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6682404 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:6682404 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:6682404 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:6682404 | pubmed:issn | 0340-6717 | lld:pubmed |
pubmed-article:6682404 | pubmed:author | pubmed-author:SchemppWW | lld:pubmed |
pubmed-article:6682404 | pubmed:author | pubmed-author:MeerBB | lld:pubmed |
pubmed-article:6682404 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:6682404 | pubmed:volume | 63 | lld:pubmed |
pubmed-article:6682404 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:6682404 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:6682404 | pubmed:pagination | 171-4 | lld:pubmed |
pubmed-article:6682404 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:6682404 | pubmed:year | 1983 | lld:pubmed |
pubmed-article:6682404 | pubmed:articleTitle | Cytologic evidence for three human X-chromosomal segments escaping inactivation. | lld:pubmed |
pubmed-article:6682404 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:6682404 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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