Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1984-7-23
pubmed:abstractText
Mononuclear cells and their fractions which were prepared from spleens removed at the time of surgery for gastric cancer were treated with mitomycin C and their effect on autochthonous peripheral blood lymphocyte responses to PHA-P and Con A was assessed in coculture experiments. Splenic mitomycin C treated mononuclear cells from certain gastric cancer patients were found to have suppressor activity on peripheral blood lymphocyte responses to PHA-P and Con A and the cells with the activity were either plastic dish adherent cells or T-enriched cells alone or both of them. The suppressor activity were more frequently detected in patients with stage IV disease and the patients with the activity tended to exhibit more decreased cell mediated immunocompetence than those without it. Splenic mitomycin C treated mononuclear cells from certain gastric cancer patients were also found to have augmenting activity on peripheral blood lymphocyte responses to PHA-P and the cells with the activity were either plastic dish adherent cells or T-enriched cells or all of plastic dish adherent cells and T- and B-enriched cells.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0301-4894
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
965-9
pubmed:dateRevised
2011-7-26
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Effect of splenic mononuclear cells on autochthonous peripheral blood lymphocyte responses to mitogens in gastric cancer patients].
pubmed:publicationType
Journal Article, English Abstract