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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
|
pubmed:dateCreated |
1984-6-1
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pubmed:abstractText |
The cellular immune response to lymphocytic choriomeningitis virus infection was found to be normal in 6-month-old mice with physiological thymus involution, while it was reduced in 18-month-old mice. The Bordetella pertussis vaccine elicited immunosuppression in 6-month-old mice with normal immunological responsiveness, while it failed to affect the physiologically diminished cellular immune response in 18-month-old mice. The extent of immunosuppression elicited by the vaccine changed parallel to its concomitant spleen hypertrophy inducing effect.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0231-4622
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
227-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6675411-Age Factors,
pubmed-meshheading:6675411-Animals,
pubmed-meshheading:6675411-Female,
pubmed-meshheading:6675411-Hypertrophy,
pubmed-meshheading:6675411-Immunity, Cellular,
pubmed-meshheading:6675411-Immunosuppression,
pubmed-meshheading:6675411-Lymphocytic Choriomeningitis,
pubmed-meshheading:6675411-Male,
pubmed-meshheading:6675411-Mice,
pubmed-meshheading:6675411-Mice, Inbred C57BL,
pubmed-meshheading:6675411-Organ Size,
pubmed-meshheading:6675411-Pertussis Vaccine,
pubmed-meshheading:6675411-Spleen,
pubmed-meshheading:6675411-Thymus Gland,
pubmed-meshheading:6675411-Vaccination
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pubmed:year |
1983
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pubmed:articleTitle |
Bacterial modulation of the cellular immune response in mice. I. The course of lymphocytic choriomeningitis virus infection in Bordetella pertussis vaccine pretreated mice with physiological thymus involution.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|