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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1984-5-18
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pubmed:abstractText |
Blood viscosity, plasma viscosity and erythrocyte filterability were studied in 46 diabetic and in 24 hyperlipidemic patients and were compared with those of a group of normal controls; 35 diabetics were type I (IDDM, 13 of whom complication-free and 22 with micro- and macroangiopathy), 11 diabetics were type II (NIDDM, 5 of whom complication-free and 6 with micro- and macroangiopathy). Erythrocyte filterability was lower in type I and II diabetes than in controls, and was also lower in diabetics with vascular complications than in complication-free patients. Erythrocyte filterability inversely correlated with HbA1c and with plasma uric acid levels. The hyperlipidemic group included 6 type IIa, 6 type IIb, 8 type IV and 4 type V patients. All hyperlipidemic patients were examined before and during diet and drug therapy. In all the hyperlipidemic patients blood viscosity inversely correlated with HDL-cholesterol, while plasma viscosity directly correlated with plasma uric acid. All these findings suggest that some hemorheological factors can play a role in the onset and progression of vascular complications of diabetes mellitus and hyperlipidemias, and that the hemorheological changes correlate with the severity of the metabolic abnormalities.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Hemoglobin A, Glycosylated,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Uric Acid
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pubmed:status |
MEDLINE
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pubmed:issn |
0390-5748
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13 Suppl 3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-79
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6672993-Blood Viscosity,
pubmed-meshheading:6672993-Cholesterol,
pubmed-meshheading:6672993-Cholesterol, HDL,
pubmed-meshheading:6672993-Diabetes Mellitus,
pubmed-meshheading:6672993-Diabetic Angiopathies,
pubmed-meshheading:6672993-Erythrocytes,
pubmed-meshheading:6672993-Hemoglobin A, Glycosylated,
pubmed-meshheading:6672993-Humans,
pubmed-meshheading:6672993-Hyperlipoproteinemias,
pubmed-meshheading:6672993-Lipoproteins, HDL,
pubmed-meshheading:6672993-Rheology,
pubmed-meshheading:6672993-Ultrafiltration,
pubmed-meshheading:6672993-Uric Acid
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pubmed:year |
1983
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pubmed:articleTitle |
[Correlation of metabolic and hemorrheological parameters in diabetes and hyperlipidemia].
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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