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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1984-4-27
|
| pubmed:abstractText |
Ten patients with idiopathic pituitary dwarfism were treated with methionyl human growth hormone (met-hGH) produced by recombinant DNA technology. They were given 0.5 IU/kg/week of met-hGH for three months. There were no significant changes in physical, blood, urine examinations. Their height increased between 1.5 and 2.7 cm during the 3 months of treatment, which was calculated to be equivalent 6.0 and 10.8 cm per year with a mean increase of 8.7 cm. Anti-hGH antibody was observed in all patients between one and two months of treatment with a titer between 10(1)X and 10(4)X. In spite of the formation of antibodies, the growth rate did not decrease in 7 of the 10 cases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0013-7219
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
30
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
523-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6671456-Adolescent,
pubmed-meshheading:6671456-Antibodies,
pubmed-meshheading:6671456-Child,
pubmed-meshheading:6671456-Dwarfism, Pituitary,
pubmed-meshheading:6671456-Female,
pubmed-meshheading:6671456-Growth Hormone,
pubmed-meshheading:6671456-Human Growth Hormone,
pubmed-meshheading:6671456-Humans,
pubmed-meshheading:6671456-Male
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Treatment of idiopathic pituitary dwarfism with methionyl human growth hormone.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|