Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
1984-4-26
pubmed:abstractText
Investigations of the peripheral capillary resistance with the congestion test after Rumpel-Leede resulted in a maximally increased vascular fragility in 172 diabetics in 72% of the cases and in 54 test persons with healthy metabolism in 11% of the cases. Clear sex or age relations could not be proved. The high proportion of pathological test results already after a short duration of diabetes (beyond the 5th year 75%) and in ophthalmoscopically not yet provable retinopathy (70%) renders evident the increased capillary fragility as a symptom of the functional prephase of the specific microangiopathy and at the same time confirms its generalized character. In 115 diabetics with high-degree pathological congestion test (IVb) a 4-week treatment with 750 mg calcium dobesilate led in 94 cases to an improvement of the findings, in 17 patients to a complete normalization. On the basis of this result as well as of pathogenetic considerations calcium dobesilate offers itself as an adjuvant treatment measure which is early to be used. The influence of a simultaneously present hypertension on the development of microangiopathy became clear at the significantly more frequent pathological and medicamentously essentially worse influencible capillary resistance.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0044-2542
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
633-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Capillary fragility in diabetics and its modification by calcium dobesilate].
pubmed:publicationType
Journal Article, English Abstract