Linked Life Data

6670057

Source:http://linkedlifedata.com/resource/pubmed/id/6670057

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-4-25
pubmed:abstractText
This study was carried out to determine whether hepatic triglyceride (TG) synthesis is a major determinant in the development of fatty liver induced by chronic ethanol ingestion. For this purpose, the degree to which the 2-monoglyceride (MG) backbone of dietary fat was retained in the accumulated TG of fatty liver was examined. Triglycerides were isolated from diet and from the liver and plasma of rats maintained for four weeks on a Lieber-DeCarli liquid ethanol diet. Pancreatic lipase hydrolysis of the TG from these three sources was carried out and the MG produced was analyzed for the fatty acid composition. Almost all of TG in fatty liver and that released to plasma retained the MG structure which originated from diet fat. This result demonstrates that the de novo glyceride synthesis or transacylation reactions do not have a major role in the production of TG in alcohol-induced fatty liver.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0191-8877
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
355-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Extent of retention of 2-monoglyceride backbone of diet fat in alcohol-induced fatty liver.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.