Linked Life Data

6669081

Source:http://linkedlifedata.com/resource/pubmed/id/6669081

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-4-24
pubmed:abstractText
The object of this work was to find out whether Candida tropicalis can be used for monochlorophenol degradation. Phenol monooxygenase and pyrocatechase, enzymes involved in preparatory phenol metabolism were shown to catalyse transformation of 3- and 4-chlorophenols. Phenol monooxygenase catalyses hydroxylation of 3- and 4-chlorophenols to 4-chloropyrocatechol which yields beta-chloromuconic acid under the action of pyrocatechase. Synthesis of phenol monooxygenase is induced by 3- and 4-chlorophenols. beta-Chloromuconic acid is a terminal product of 3- and 4-chlorophenol transformation under neutral conditions. In a weakly acid medium (the Rieder medium, phosphate buffer, pH 5.5), transformation of these chlorophenols terminates with spontaneous lactonization of beta-chloromuconic acid and its dehalogenation. C. tropicalis hardly transforms 2-chlorophenol although certain oxygen uptake occurs in its presence. 3- and 4-chlorophenols are not nutrient sources for C. tropicalis. The yeast has not been adapted to 3- and 4-chlorophenols as sole nutrient sources.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0026-3656
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
956-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Monochlorophenols as enzyme substrates for the preparatory metabolism of phenol in Candida tropicalis yeasts].
pubmed:publicationType
Journal Article, English Abstract