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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
1984-3-21
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pubmed:abstractText |
A release of the MB fraction of creatine kinase (CK) enzyme into the serum due to myocardial manipulation and trauma occurs in patients undergoing cardiac surgery. Thus, the appearance of CK-MB activity as such is not sufficient to indicate of perioperative myocardial infarction. The mean (+/- SD) serum CK-MB isoenzyme level was 95 +/- 103 U/l 18 hours after aortic or mitral valve replacement in 76 patients. Thirteen patients undergoing closure of an atrial septal defect served as controls. They had a significantly lower (p less than 0.01) isoenzyme level postoperatively: 45 +/- 39 U/l. Two patients had the ECG changes of definite myocardial infarction after valve replacement and they also showed high CK-MB values, while the other patients with high enzyme level had no ECG signs suggesting acute infarction. CK-MB values correlated with the aortic cross-clamping time (r = 0.39, p less than 0.001) and weakly with the precordial ECG voltage of SV1 + RV5 (r = 0.25, p less than 0.01). While these findings may reflect the sensitivity of a thick myocardial wall to ischaemia during surgery, the postoperative recovery was not related to the serum CK-MB level.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0003-4762
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189-93
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6667015-Adult,
pubmed-meshheading:6667015-Aged,
pubmed-meshheading:6667015-Aortic Valve,
pubmed-meshheading:6667015-Creatine Kinase,
pubmed-meshheading:6667015-Electrocardiography,
pubmed-meshheading:6667015-Heart Septal Defects, Atrial,
pubmed-meshheading:6667015-Heart Valve Prosthesis,
pubmed-meshheading:6667015-Humans,
pubmed-meshheading:6667015-Isoenzymes,
pubmed-meshheading:6667015-Middle Aged,
pubmed-meshheading:6667015-Mitral Valve,
pubmed-meshheading:6667015-Myocardial Infarction,
pubmed-meshheading:6667015-Postoperative Complications
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pubmed:year |
1983
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pubmed:articleTitle |
Serum CK-MB isoenzyme after aortic and mitral valve replacements.
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pubmed:publicationType |
Journal Article
|