Linked Life Data

6662172

Source:http://linkedlifedata.com/resource/pubmed/id/6662172

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-2-29
pubmed:abstractText
A randomized, blind cross-over study was carried out in 12 patients with bronchial asthma to determine whether the bronchodilating effect of a metered dose inhaler was influenced by increasing the metering volume from 25 microliters to 50 microliters, or by increasing the vapour pressure from 374 kPa to 502 kPa. Spirometry, heart rate and tremor were recorded 15 min after terbutaline sulphate 31 micrograms, 63 micrograms, 125 micrograms, 250 micrograms, 2 X 250 micrograms and 5 X 250 micrograms. There was no significant difference in any of the variables recorded i.e. in forced expiratory volume in one second, forced vital capacity or in airflows when 50% and 25% of the FVC remained to be exhaled from the total lung capacity. It is concluded that the bronchodilating effect of a beta 2-agonist from a metered dose inhaler is not substantially affected by changes in metering volume or vapor pressure within the limits studied.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0031-6970
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
735-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Bronchodilator effect of terbutaline aerosol is not affected by propellant vapour pressure or dose volume.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial