|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
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|
pubmed:dateCreated |
1984-2-14
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|
pubmed:abstractText |
Soluble complexes of an NH2-terminal disulphide knot of fibrin (N-DSK alpha) with fragment D, its dimer (DD) and fibrinogen were detected by sepharose gel filtration. The main component of fragment D and N-DSK alpha mixture is represented by a specific complex eluted as a separate peak. Inactive fibrinogen N-DSK produce no complexes with fragment D. The DD-N-DSK complex is eluted together with free DD. Soluble oligomers which are partially eluted in the free column volume as well as insoluble aggregates of N-DSK alpha and fibrinogen are formed in mixture of these components. The molar D/N-DSK alpha ratio was determined in complexes isolated from mixtures with different D/N-DSK alpha ratio. A conclusion is drawn that a N-DSK alpha molecule may bind at most two fragment D molecules.
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pubmed:language |
rus
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:issn |
0201-8470
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
55
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
614-21
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
|
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pubmed:articleTitle |
[Soluble complexes of the NH2-terminal disulfide knot of fibrin with molecules containing D domains].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|
