Linked Life Data

6656319

Source:http://linkedlifedata.com/resource/pubmed/id/6656319

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1984-2-24
pubmed:abstractText
5he effect of age on the immunological responses to Babesia microti infection in the mouse was investigated. Aged mice experienced reduced and delayed peak parasitemias compared to younger animals; however, the old mice failed to clear the parasites from the blood and experienced fluctuating parasitemias until death. Babesiosis produced suppression of responses to nonspecific B and T cell mitogens concomitant with rising autoantibody plaque forming cells reactive with untreated and bromelain modified mouse erythrocytes. Similar observations of increased susceptibility to babesiosis with age and immunosuppression have been made in human babesiosis. Thus, the murine model for this hemoprotozoan infection is faithful to the human immunological responses.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0047-6374
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
357-69
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
The effect of age on the infection and immunoresponsiveness of mice to Babesia microti.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't