Linked Life Data

6656286

Source:http://linkedlifedata.com/resource/pubmed/id/6656286

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-2-22
pubmed:abstractText
We consider the classic Stein (1965) model for stochastic neuronal firing under random synaptic input. Our treatment includes the additional effect of synaptic reversal potentials. We develop and employ two numerical methods (in addition to Monte Carlo simulations) to study the relation of the various parameters of the model to the shape of the theoretical interspike interval distribution. Contrary to the results of Tuckwell (1979) we are unable to account, on the basis of substantial synaptic inhibition and with parameter settings in the known physiologic range, for experimental interspike interval distributions which exhibit large coefficients of variation or bimodality. We therefore introduce a time varying threshold into the model, which readily allows for such distributions and which has physiological justification.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-5193
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
345-68
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
A theoretical basis for large coefficient of variation and bimodality in neuronal interspike interval distributions.
pubmed:publicationType
Journal Article