Linked Life Data

6655434

Source:http://linkedlifedata.com/resource/pubmed/id/6655434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-2-15
pubmed:abstractText
These experiments describe further investigations into the effects of vitamin A on regenerating limbs. The effects of different retinoids, the time of administration, concentration of vitamin A and histological, autoradiographic and histochemical studies are reported. The most obvious result of vitamin A treatment is to cause proximal elements to regenerate from distal amputation levels, that is to cause serial reduplication of pattern in the proximodistal axis. Retinoic acid was the most potent of the analogues tested and longer times of administration or higher concentrations cause a greater amount of serial reduplication. Various tissue changes have been found which include the inhibition of cell division, loss of cartilage metachromasia, changes in the mucous-secreting properties of the epidermis and an increased packing in the blastemal cells. The significance of these cellular effects in relation to the pattern-formation changes is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-0752
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
273-95
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The effect of vitamin A on the regenerating axolotl limb.
pubmed:publicationType
Journal Article