Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1984-2-24
|
pubmed:abstractText |
Intracellular recordings were made from inner hair cells and basilar membrane motion was measured at a similar place, but in different preparations, in the first turn of the guinea pig cochlea. Potential recordings were made using glass microelectrodes and mechanical measurements were made using the Mössbauer technique. Intensity functions of DC receptor potential and basilar membrane velocity in animals with good and poor thresholds are presented. In animals with good thresholds, stimuli at and above the characteristic frequency produce similarly compressive input-output functions for both inner hair cell receptor potentials and basilar membrane motion. However, for frequencies lower than the characteristic frequency, receptor potential input-output functions obtained from animals in good and poor condition show saturation at high stimulus intensities at which basilar membrane motion is linear. This discrepancy is believed to be due to a nonlinear inner hair cell transduction mechanism. We propose that nonlinearity observed in receptor potential input-output functions is a consequence of the simple cascading of a frequency-dependent nonlinear mechanical input and a frequency-independent nonlinear transduction process.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0001-4966
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
74
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1734-41
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6655131-Action Potentials,
pubmed-meshheading:6655131-Animals,
pubmed-meshheading:6655131-Auditory Threshold,
pubmed-meshheading:6655131-Basilar Membrane,
pubmed-meshheading:6655131-Cochlear Microphonic Potentials,
pubmed-meshheading:6655131-Ear, Inner,
pubmed-meshheading:6655131-Guinea Pigs,
pubmed-meshheading:6655131-Hair Cells, Auditory,
pubmed-meshheading:6655131-Hair Cells, Auditory, Inner
|
pubmed:year |
1983
|
pubmed:articleTitle |
A comparison between basilar membrane and inner hair cell receptor potential input-output functions in the guinea pig cochlea.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|