Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-2-20
pubmed:abstractText
The present study was undertaken to examine the abnormality in motor function of newly found mutant mice electrophysiologically. It was found that their motor nerve fibers progressively fail to conduct action potentials, while impulse conduction in the sensory fibers remains intact. The conduction block of motor fibers proceeded in the proximo-distal direction. Excitation of the motor fibers was blocked by raising the extracellular Ca2+ or Mg2+ concentration in vitro. It is concluded that this new mutant mouse has a motor neuron disease of the 'dying-forward' type.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:volume
312
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
139-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
A new mutant mouse with motor neuron disease.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't