Linked Life Data

6648042

Source:http://linkedlifedata.com/resource/pubmed/id/6648042

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-1-27
pubmed:abstractText
The association of serum LDL cholesterol and the LDL/HDL cholesterol ratio, the major positive risk factors of coronary heart disease, to hepatic microsomal enzyme induction assessed by liver cytochrome P-450, was investigated in 18 subjects who were treated with inducing anticonvulsants. In subjects with normal liver histology, LDL cholesterol and the LDL/HDL cholesterol ratio were inversely proportional to the magnitude of induction. Strong induction was associated with a low LDL cholesterol level. The serum cholesterol distribution profile and the low LDL/HDL cholesterol ratio associated with induction are characteristic of low risk of coronary heart disease. The present findings support studies showing a positive association between HDL cholesterol and induction and suggesting a new therapeutic approach to atherosclerotic vascular disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0034-5164
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
173-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Inverse relationship of serum LDL cholesterol and the LDL/HDL cholesterol ratio to liver microsomal enzyme induction in man.
pubmed:publicationType
Journal Article