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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1984-1-27
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pubmed:abstractText |
An improved method for the hydrolysis of long chain bases from gangliosides with aqueous acetonitrile-HCl is described. The long chain bases released from brain gangliosides were derivatized with biphenylcarbonylchloride and resolved by high performance liquid chromatography on a C18 reversed-phase column. Components of individual peaks were identified by gas-liquid chromatography-mass spectrometry as their trimethylsilyl derivatives. The acetonitrile-HCL hydrolysis procedure resulted in no formation of O-methyl ethers of long chain bases and a significant decrease in the level of secondary products.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-2275
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1389-97
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6644189-Acetonitriles,
pubmed-meshheading:6644189-Brain Chemistry,
pubmed-meshheading:6644189-Chromatography, High Pressure Liquid,
pubmed-meshheading:6644189-Gangliosides,
pubmed-meshheading:6644189-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:6644189-Humans,
pubmed-meshheading:6644189-Hydrochloric Acid,
pubmed-meshheading:6644189-Hydrolysis
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pubmed:year |
1983
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pubmed:articleTitle |
Acetonitrile-hydrochloric acid hydrolysis of gangliosides for high performance liquid chromatographic analysis of their long chain bases.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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