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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1984-1-7
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pubmed:abstractText |
Three commercial latex kits, IBL, MYCO-Immune, and IMMY, for the detection of cryptococcal antigen were compared in regard to sensitivity, specificity, and height of antigen titers. A total of 218 cerebrospinal fluid and 79 serum specimens from 239 patients were included. Twenty-two patients had culture-proven disseminated cryptococcosis. Both the IBL and MYCO-Immune kits had sensitivities of 100%, and the IMMY kit had sensitivities of 82.6 and 45.4% in CSF and serum specimens, respectively. There was one false-positive reaction in serum with the MYCO-Immune kit and one false-negative reaction on screen only with all three kits. Rheumatoid factor-containing sera were used to check the agglutination titers between matching anti-cryptococcal globulin reagents and normal globulin reagents. The finding that agglutination titer with anti-cryptococcal globulin reagents was fourfold higher than with normal globulin reagents in the MYCO-Immune kit is considered to be a cause for a false-positive reaction in serum.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6643665-14076914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6643665-4811791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6643665-4816794,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6643665-5094497,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6643665-7153347,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6643665-7334079
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0095-1137
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1127-30
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6643665-Antigens, Bacterial,
pubmed-meshheading:6643665-Cryptococcosis,
pubmed-meshheading:6643665-Cryptococcus,
pubmed-meshheading:6643665-False Negative Reactions,
pubmed-meshheading:6643665-False Positive Reactions,
pubmed-meshheading:6643665-Humans,
pubmed-meshheading:6643665-Latex Fixation Tests,
pubmed-meshheading:6643665-Reagent Kits, Diagnostic
|
pubmed:year |
1983
|
pubmed:articleTitle |
Comparison of three commercial cryptococcal latex kits for detection of cryptococcal antigen.
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pubmed:publicationType |
Journal Article,
Comparative Study
|