Linked Life Data

6642409

Source:http://linkedlifedata.com/resource/pubmed/id/6642409

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1984-1-7
pubmed:abstractText
Sprague-Dawley (SD) rats kept at room temperature do have a higher growth rate and food conversion compared to Wistar rats. Mean hormone level in blood samples collected every four hours during a 24 hour period do differ between both strain of rats. So, the mean circulating levels of T3, T4 and corticosterone are significantly lower, whereas prolactin concentrations are higher in SD-rats. Following acute cold exposure comparable increases in plasma T3 and T4 are seen in both strains after 3-5 hours. Prolactin plasma concentrations are decreased after 5 and 9 hours but only in SD-rats, whereas they remain unchanged in Wistars. Acclimation to 4 degrees C during 3 and 8 weeks resulted in a decreased growth rate of the SD-rats, which becomes comparable to Wistar animals, but food conversion is lower and food intake higher in SD-rats. A decrease in circulating levels of T4 is present in Wistars resulting in a significantly lower figure at 8 weeks of cold acclimation, whereas at the same time T3 is increased. Prolactin is decreased in SD-rats and increased in Wistars causing at 8 weeks of cold acclimation higher levels in Wistars. Corticosterone levels remain higher in Wistar rats and are comparable to rats kept at room temperature. It is concluded that the differences in growth rate, food conversion and food intake are related to the endocrine differences and responses observed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0018-5043
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
491-8
pubmed:dateRevised
2009-2-19
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Endocrine differences between the Wistar and Sprague-Dawley laboratory rat: influence of cold adaptation.
pubmed:publicationType
Journal Article, Comparative Study