Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-1-27
pubmed:abstractText
Fibroblasts from hamster embryos were serially cultivated in vitro and their evolution followed from a morphological, physiological and biochemical point of view. After an exponential growth for about 20 passages, cells entered the ageing phase which ended up after 29-34 passages. From our observations, it seems that the arrest of growth results from two different phenomena: first, the typically fibroblastic cells may undergo a stochastic ageing process; second, some of these cells evolve into a terminal differentiation process, characterized by a different non-fibroblastic phenotype.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0531-5565
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
223-40
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Ageing of hamster embryo fibroblasts as the result of both differentiation and stochastic mechanisms.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't