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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1978-9-1
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pubmed:abstractText |
Steroid hydroxylases (SAH) are inducible in cultured human lymphocytes following treatment with estradiol-17beta. The enzyme systems induced are carbon monoxide sensitive and convert estradiol-17beta to a metabolite chromatographically indistinguishable from estriol. The level of inducibility of SAH varies drastically over a normal menstrual cycle with maximum induction in the late follicular phase and minimum induction during the luteal phase. The use of an oral contraceptive containing both a synthetic progestogen and ethynyl estradiol reduced SAH induction levels to those typically seen during the luteal phase of the menstrual cycle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0039-128X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:663955-Cells, Cultured,
pubmed-meshheading:663955-Contraceptives, Oral,
pubmed-meshheading:663955-Contraceptives, Oral, Synthetic,
pubmed-meshheading:663955-Enzyme Induction,
pubmed-meshheading:663955-Estradiol,
pubmed-meshheading:663955-Female,
pubmed-meshheading:663955-Humans,
pubmed-meshheading:663955-Lymphocytes,
pubmed-meshheading:663955-Menstruation,
pubmed-meshheading:663955-Ovulation,
pubmed-meshheading:663955-Steroid Hydroxylases
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pubmed:year |
1978
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pubmed:articleTitle |
Steroid hydroxylase induction in cultured human lymphocytes: effects of the menstrual cycle.
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pubmed:publicationType |
Journal Article
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