Linked Life Data

6639096

Source:http://linkedlifedata.com/resource/pubmed/id/6639096

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1983-12-17
pubmed:abstractText
The relationship between natural killer (NK) activity of peripheral blood lymphocytes and serum C-reactive protein (CRP) concentration was analysed in patients with carcinoma of the lung and metastatic pulmonary tumors. Significant reverse correlation (r=-0.43) was found between NK activity against OAT cells or K-562 cells and serum CRP concentration. For the elucidation of the mechanism of suppressive activity of CRP against NK activity, in vitro effects of CRP on NK activity was studied. Relative NK activity compared to control decreased to 23.3 +/- 5.6% in experiment adding 1.0 mg/dl of CRP into NK assay mixture (p less than 0.001). Relative NK activity was also strongly inhibited in experiment preincubating lymphocytes with CRP. The decrease of NK activity with CRP was depending on the concentration of CRP.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0385-0684
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2341-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Effect of C-reactive protein on natural killer activity].
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't