Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1983-12-17
pubmed:abstractText
An important source of variability of experimental results in inhalation toxicology originates from the nonuniformity of chamber concentrations. Two horizontal flow inhalation chambers were used in evaluating the effect of cage rotation within each chamber on the amount of alpha-quartz deposited in the lungs of male Fischer 344 rats. The alpha-quartz lung burden was determined by quantitative X-ray diffraction. A carefully designed animal rotation schedule significantly reduced the variability in the amount of alpha-quartz deposited in the animals, thereby minimizing effects of chamber nonuniformity due either to design or dust generator characteristics.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0002-8894
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
655-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effectiveness of animal rotation in achieving uniform dust exposures and lung dust deposition in horizontal flow chambers.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.