Linked Life Data

6637461

Source:http://linkedlifedata.com/resource/pubmed/id/6637461

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
1983-12-20
pubmed:abstractText
The nasal mucosal blood flow was determined by means of the 133Xe wash-out method in an early stage of acute rhinitis and in health and the effect of a topical decongestant (oxymetazoline) was evaluated. During an early stage of acute rhinitis, a statistically significant increase of blood flow was found. The topical decongestant in therapeutically recommended doses decreased the blood flow significantly in acute rhinitis as well as in healthy subjects. The effect was more pronounced in acute rhinitis. The effect of oxymetazoline was dose dependent and a statistically significant decrease was found in doses of about 1/50 of the therapeutically recommended. The clinical implication is that it might be possible to reduce the dose of the decongestant in order to minimize the negative side effect of a decreased blood flow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6489
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
523-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
The effect of topical decongestant on blood flow in normal and infected nasal mucosa.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't