Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1983-12-20
pubmed:abstractText
According to its aromatic nitro group acetylaminonitropropoxybenzene (Falimint) can be determined polarographically. The typical behavior of the nitro group becomes evident by the elektrochemical reduction. The investigation has shown two phases of reduction with pH-depended half-wave-potential shifts, so that a two-step mechanism is conceivable. Using direct current polarography the substance is determined in a concentration range from 1 to 100 micrograms/ml. Low elektroaktive background signals within the potential range the four-electron reduction step are the basis for the determination of the active agent in saliva, urine and blood plasma without any extracting procedures. It is possible to identify the substance by means of oscilloand square-wave-polarography. The resulting polarogrammes are typically for the p-nitrophenyl structure. Further a new quantitativ polarographic method, named sample-DC-polarography on the stationary mercury electrode is discussed for the determination of Falimint in blood plasma without any steps of separation and cleaning in the concentration range of 0,1-3,0 micrograms/ml.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0031-7144
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
527-30
pubmed:dateRevised
2007-1-29
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Pharmaceutical and biopharmaceutical evaluation of acetylaminonitropropoxybenzolum (Falimint). 3: Polarographic analysis and determination of active agents].
pubmed:publicationType
Journal Article, English Abstract