Linked Life Data

6630414

Source:http://linkedlifedata.com/resource/pubmed/id/6630414

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1983-12-21
pubmed:abstractText
Calcitonin (CT) levels were determined in urine specimens from normal subjects and patients with pseudohypoparathyroidism type I (PHP), idiopathic hypoparathyroidism (IHP), pseudopseudohypoparathyroidism (PPHP), and surgical hypoparathyroidism (SHP). Urinary CT was measured by RIA after extraction of urine by gel chromatography on a 0.8 X 20-cm column of Bio-Gel P-2. The urinary CT level ranged from 420-1000 pg/mg creatinine (Cr; mean +/- SD, 631 +/- 229) in PHP (n = 6), from 50-270 (131 +/- 92) in IHP (n = 6), and from 35-93 (66 +/- 27) in SHP (n = 6), and was 185 pg/mg Cr in one patient with PPHP. The mean value in PHP was significantly (P less than 0.001) higher, and that in SHP was significantly (P less than 0.05) lower, than those in the age-matched normal subjects. In each patient with PHP and IHP before and after treatment with 1 alpha-hydroxycholecalciferol, urinary CT levels fluctuated between 700-1370 pg/mg Cr in PHP and from 43-195 pg/mg Cr in IHP. Increased urinary excretion of CT in patients with PHP suggests that CT secretion may be enhanced in this disease. The biological role of CT in PHP remains to be clarified.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0021-972X
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1216-20
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Differentiation of pseudo- and idiopathic hypoparathyroidism by measuring urinary calcitonin.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't