Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-12-20
pubmed:abstractText
A systematic search for chromosome pairing defects in foetal mouse oocytes has been carried out in two different strains (Swiss and CBA/Ca) over days 15-19 of gestation and on day 1 post-partum. The aim was to seek direct cytological evidence for a "production line" of oocyte development, or the occurrence of pairing anomalies at meiotic prophase that might lead, in the adult female, to nondisjunction at anaphase I. No evidence for either was found. The data argue against the "production line" hypothesis as the basis for maternal age-related increases in aneuploidy in the mouse. Attempts to analyse chiasmata in oocytes at diplotene were unsuccessful.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0009-5915
pubmed:author
pubmed:issnType
Print
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
184-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Meiosis in the foetal mouse ovary. II. Oocyte development and age-related aneuploidy. Does a production line exist?
pubmed:publicationType
Journal Article