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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1983-12-20
|
| pubmed:abstractText |
An isodicentric X-chromosome (idic(X)(pter leads to q23::q23 leads to pter)) was found in a phenotypically normal 30-year-old female with symptoms of premature menopause. A study of DNA replication revealed that in a proportion of cells there was an asymmetric pattern of replication. The region with the inactive centromere had a tendency to replicate later than the portion with the functioning centromere.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0009-9163
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
180-3
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6627721-Adult,
pubmed-meshheading:6627721-Centromere,
pubmed-meshheading:6627721-Chromosome Aberrations,
pubmed-meshheading:6627721-DNA Replication,
pubmed-meshheading:6627721-Dosage Compensation, Genetic,
pubmed-meshheading:6627721-Female,
pubmed-meshheading:6627721-Humans,
pubmed-meshheading:6627721-Menopause, Premature,
pubmed-meshheading:6627721-X Chromosome
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Replication and inactivation of an isodicentric X: presence of an inactive centromere influences the replication patterns.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|