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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7-8
|
pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
Electrophoretic variation of sorbitol dehydrogenase has been found in Mus musculus; the SDH-1 A phenotype migrates further toward the cathode under the conditions used than the SDH-1B phenotype. Mice with the SDH-1B phenotype have enzyme activity reduced to 25% of that found in mice with the SDH-1A phenotype, but no differences in heat stability, pH profile, or Km for fructose were found. The gene Sdh-1 is inherited as an autosomal condominant located on chromosome 2, and the gene order obtained, with genetic distance calculated as percentage recombination +/- SE was Sdh-1--1.9 +/- 1.4--pa--16.4 +/- 3.6--a--3.9 +/- 1.9--bp.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-2928
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
809-17
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:6626150-Animals,
pubmed-meshheading:6626150-Chromosome Mapping,
pubmed-meshheading:6626150-Cytoplasm,
pubmed-meshheading:6626150-Genetic Linkage,
pubmed-meshheading:6626150-Isoenzymes,
pubmed-meshheading:6626150-L-Iditol 2-Dehydrogenase,
pubmed-meshheading:6626150-Mice,
pubmed-meshheading:6626150-Mice, Inbred Strains,
pubmed-meshheading:6626150-Recombination, Genetic,
pubmed-meshheading:6626150-Substrate Specificity,
pubmed-meshheading:6626150-Sugar Alcohol Dehydrogenases
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pubmed:year |
1983
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pubmed:articleTitle |
Linkage analyses and biochemical genetics of sorbitol dehydrogenase-1 (Sdh-1) in the mouse.
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pubmed:publicationType |
Journal Article,
Comparative Study
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