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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
Mycotoxin T-2 (0.5 mg/kg of body weight) was administered orally to mixed-breed beef calves. Serum protein fractions, immunoglobulin (Ig) G, IgM, and several complement protein concentrations were studied in control and toxin-treated calves. Total protein, albumin, and globulin concentrations all decreased in toxin-treated calves as compared with that in controls. Similarly, the concentrations of alpha-, beta 1-, and beta 2-globulin fractions were reduced in the toxin-treated calves more than those in controls. The IgG and IgM values were lower in toxin-treated calves than those in the controls. Complement proteins Bbov (of the alternate pathway) and the 3rd component of complement were lower in the toxin-treated calves. The fragment of Bbov activation, B gamma 2, was increased after toxin treatment, indicating that activation of the alternate complement pathway was responsible for at least some of the reduction of the 3rd component of complement.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Complement System Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Mycotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-9645
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1757-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
1983
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pubmed:articleTitle |
Effects of T-2 mycotoxin on bovine serum proteins.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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