Linked Life Data

6619811

Source:http://linkedlifedata.com/resource/pubmed/id/6619811

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-11-23
pubmed:abstractText
To investigate the frequency of natural reinfection with influenza A viruses, 55 children followed from birth along with the 44 other children and 85 adults in their families were observed for varying periods between 1975 and 1981 in the Houston Family Study. Persons infected in 1976 or early 1977 with influenza A subtype H3N2 experienced a high rate of reinfection during the 1977-78 season (63% in one group of young children) and additional reinfections in 1980-81. Persons in whom H3N2 infection was first observed in 1977-78 had little or no reinfection in 1980-81; one reinfection was observed in 1980-81 among 19 young children at risk. Only one reinfection with influenza A subtype H1N1 was observed following introduction of the virus in early 1978 despite exposure in 1978-80 and a substantial outbreak in 1980-81. Statistically significant protection from reinfection in young children followed from birth was not noted for the 1977-78 H3N2 outbreak but was present in 1979-81 for both H3N2 and H1N1 viruses. Reasons for variations in reinfection suggested by this data include 1) socioeconomic and other factors influencing intensity of exposure, 2) age at primary infection, 3) varying degrees of antigenic difference between sequential variants of a major subtype, and 4) unrecognized immunogenicity or virulence differences between subtypes and variants.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0146-6615
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-23
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Variation in frequency of natural reinfection with influenza A viruses.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.