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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
Intraspinal (i.s.) injection of 6-hydroxydopamine or 5,7-dihydroxytryptamine in newborn spontaneously hypertensive rats (SHR) resulted, in the adult animal (30-week-old), in a marked decrease of spinal cord noradrenaline (NA) or 5-hydroxytryptamine (5-HT) levels, respectively. Since both neurotoxin- and vehicle-injected rats developed full hypertension and had similar plasma catecholamine concentrations, it is concluded that in SHR neither spinal cord NA nor 5-HT play a major role in development and maintenance of hypertension.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0014-4754
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1166-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:6617819-Animals,
pubmed-meshheading:6617819-Blood Pressure,
pubmed-meshheading:6617819-Female,
pubmed-meshheading:6617819-Hypertension,
pubmed-meshheading:6617819-Male,
pubmed-meshheading:6617819-Neurons,
pubmed-meshheading:6617819-Norepinephrine,
pubmed-meshheading:6617819-Rats,
pubmed-meshheading:6617819-Rats, Inbred Strains,
pubmed-meshheading:6617819-Serotonin,
pubmed-meshheading:6617819-Spinal Cord
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pubmed:year |
1983
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pubmed:articleTitle |
Effects of neurochemical lesions restricted to spinal cord monoaminergic neurons on blood pressure and sympathetic activity of spontaneously hypertensive rats.
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pubmed:publicationType |
Journal Article
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