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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1983-10-8
|
| pubmed:abstractText |
The purpose of this study was to examine the incidence and implications of false-negative exercise electrocardiographic results among 216 consecutive patients with angiographically documented coronary artery disease (50 percent diameter narrowing or greater of one or more vessels). Exercise electrocardiography gave negative (false-negative) results in 23 patients and positive (true-positive) results in 102 patients, and were nondiagnostic in the rest. Exercise thallium-201 imaging was performed in 88 patients. The extent of coronary artery disease was quantitated by a scoring system that takes into consideration the degree and site of narrowing in the major vessels and their branches. The exercise heart rate was higher in patients with false-negative than in patients with true-positive exercise electrocardiographic results (161 +/- 18 versus 133 +/- 24 beats per minute, mean +/- SD; p less than 0.0001). Q-wave infarction was present in two patients (9 percent) with false-negative and 20 patients (20 percent) with true-positive exercise electrocardiographic results (p = NS); left ventricular asynergy at rest was observed in 13 patients (57 percent) with false-negative and in 74 patients (74 percent) with true-positive results (p = NS). Patients with false-negative results had less extensive coronary disease than did patients with true-positive results (score 5.8 +/- 3.6 versus 9.2 +/- 5.0; p = 0.0025). Angina during exercise was less frequent in patients with false-negative results (p less than 0.01). Abnormal exercise thallium-201 images were seen in 15 of 20 patients (75 percent) with false-negative results and in 56 of 68 patients (82 percent) with true-positive results (p = NS). It is concluded that (1) false-negative exercise electrocardiographic results are infrequent (10 percent) among patients with coronary artery disease and are associated with less extensive coronary artery disease; (2) the frequency of Q-wave infarction and left ventricular asynergy is the same in patients with false-negative results as in patients with true-positive exercise electrocardiographic results; (3) exercise thallium images can identify 75 percent of patients with coronary disease and false-negative results of exercise electrocardiography.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0002-9343
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
75
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
439-44
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:6614030-Adult,
pubmed-meshheading:6614030-Angina Pectoris,
pubmed-meshheading:6614030-Angiography,
pubmed-meshheading:6614030-Coronary Angiography,
pubmed-meshheading:6614030-Coronary Disease,
pubmed-meshheading:6614030-Electrocardiography,
pubmed-meshheading:6614030-False Negative Reactions,
pubmed-meshheading:6614030-Female,
pubmed-meshheading:6614030-Heart Ventricles,
pubmed-meshheading:6614030-Humans,
pubmed-meshheading:6614030-Male,
pubmed-meshheading:6614030-Middle Aged,
pubmed-meshheading:6614030-Perfusion,
pubmed-meshheading:6614030-Physical Exertion,
pubmed-meshheading:6614030-Radioisotopes,
pubmed-meshheading:6614030-Thallium
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Implications of normal exercise electrocardiographic results in patients with angiographically documented coronary artery disease. Correlation with left ventricular function and myocardial perfusion.
|
| pubmed:publicationType |
Journal Article
|