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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1984-8-30
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pubmed:abstractText |
The immune response is a complex series of cellular interactions, which is controlled by several regulatory mechanisms to insure an appropriate response. One of the most important mechanisms of control is the suppressor T cell immunoregulatory circuit. The immune response is presented in detail and examined from three different perspectives: 1) a clinical disease in which it is markedly abnormal--namely, the acquired immune deficiency syndrome or AIDS, 2) a clinical disease in which no systemic abnormality is apparent but where a local derangement in immunoregulation may be important--namely, idiopathic uveitis, and 3) a situation in which it is purposefully altered by medications for therapeutic purposes. Three drugs currently used in the treatment of uveitis--prednisone, cyclophosphamide, and cyclosporine--will be examined and compared.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0161-6420
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
655-65
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6611528-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:6611528-Antibodies, Monoclonal,
pubmed-meshheading:6611528-Antibody Formation,
pubmed-meshheading:6611528-B-Lymphocytes,
pubmed-meshheading:6611528-Cyclophosphamide,
pubmed-meshheading:6611528-Cyclosporins,
pubmed-meshheading:6611528-Humans,
pubmed-meshheading:6611528-Immunity, Cellular,
pubmed-meshheading:6611528-Macrophages,
pubmed-meshheading:6611528-Prednisone,
pubmed-meshheading:6611528-Retinitis,
pubmed-meshheading:6611528-T-Lymphocytes,
pubmed-meshheading:6611528-Uveitis
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pubmed:year |
1984
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pubmed:articleTitle |
Immunologic insights into uveitis and retinitis: the immunoregulatory circuit.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|