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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-6-7
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pubmed:abstractText |
Immunological evaluation of 20 patients with retinitis pigmentosa (RP) revealed significantly diminished circulating T-lymphocyte numbers and function and a high frequency of serum antibodies to human IgG in comparison with a healthy matched control population. However, these differences were due to severely abnormal results found in one subpopulation within the total patient group; this dichotomy was unrelated to the mode of inheritance or clinical severity of RP in individual patients. Thus, RP appears to be a syndrome rather than a disease and includes a form characterized by defective immunity. Whether this is involved in the pathogenesis of the retinal degenerative process is conjectural.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0090-1229
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
254-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6609039-Antibodies, Anti-Idiotypic,
pubmed-meshheading:6609039-Humans,
pubmed-meshheading:6609039-Immunologic Deficiency Syndromes,
pubmed-meshheading:6609039-Leukocyte Count,
pubmed-meshheading:6609039-Lymphocyte Activation,
pubmed-meshheading:6609039-Lymphokines,
pubmed-meshheading:6609039-Retinitis Pigmentosa,
pubmed-meshheading:6609039-Rosette Formation,
pubmed-meshheading:6609039-T-Lymphocytes,
pubmed-meshheading:6609039-Visual Fields
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pubmed:year |
1984
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pubmed:articleTitle |
One subset of patients with retinitis pigmentosa has immunologic defects.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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