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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-2-14
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pubmed:abstractText |
Interstitial pneumonitis developed in a patient who had received a cumulative dose of 985 g of amiodarone in nine years. No other cause for pneumonitis was found. The following findings favor an immunologic mechanism of hypersensitivity due to amiodarone: positive skin and basophil degranulation tests with amiodarone; lymphocytosis and inverted ratio of helper/suppressor T lymphocytes in bronchoalveolar lavage fluid; secretion of leukocyte inhibitory factor, as shown by the inhibition of migration of peripheral blood leukocytes; and positive lymphoblastic transformation in the presence of amiodarone.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
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pubmed:issn |
0012-3692
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6606534-Aged,
pubmed-meshheading:6606534-Alveolitis, Extrinsic Allergic,
pubmed-meshheading:6606534-Amiodarone,
pubmed-meshheading:6606534-Benzofurans,
pubmed-meshheading:6606534-Cell Migration Inhibition,
pubmed-meshheading:6606534-Drug Hypersensitivity,
pubmed-meshheading:6606534-Humans,
pubmed-meshheading:6606534-Leukocyte Count,
pubmed-meshheading:6606534-Leukocytes,
pubmed-meshheading:6606534-Male,
pubmed-meshheading:6606534-Pulmonary Fibrosis,
pubmed-meshheading:6606534-Skin Tests,
pubmed-meshheading:6606534-T-Lymphocytes,
pubmed-meshheading:6606534-Time Factors
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pubmed:year |
1984
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pubmed:articleTitle |
Amiodarone-induced hypersensitivity pneumonitis. Evidence of an immunological cell-mediated mechanism.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|