| pubmed-article:6605372 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6605372 | lifeskim:mentions | umls-concept:C0121772 | lld:lifeskim |
| pubmed-article:6605372 | lifeskim:mentions | umls-concept:C0026724 | lld:lifeskim |
| pubmed-article:6605372 | lifeskim:mentions | umls-concept:C0003261 | lld:lifeskim |
| pubmed-article:6605372 | lifeskim:mentions | umls-concept:C0042196 | lld:lifeskim |
| pubmed-article:6605372 | lifeskim:mentions | umls-concept:C1518896 | lld:lifeskim |
| pubmed-article:6605372 | lifeskim:mentions | umls-concept:C0006935 | lld:lifeskim |
| pubmed-article:6605372 | pubmed:issue | 5 Pt 1 | lld:pubmed |
| pubmed-article:6605372 | pubmed:dateCreated | 1983-12-17 | lld:pubmed |
| pubmed-article:6605372 | pubmed:abstractText | The simultaneous serum and mucosal antibody response to parenteral vaccination with the Haemophilus influenzae type b (Hib) polysaccharide capsule (PRP) was evaluated in a group of 10 children and nine adults. All subjects responded to parenteral vaccination with an increase in serum anticapsular antibody. The children's preimmunization anti-PRP antibody level (mean = 0.04 microgram/ml) and 3 wk postimmunization level (mean = 19.3 micrograms/ml) were lower than the adults' (preimmunization mean = 1.5 microgram/ml; postimmunization mean = 81.2 micrograms/ml). Eight of 10 children and seven of nine adults also developed a rise in antibody in nasal secretions. The children's mean nasal preimmunization level was 0.74 microgram/mg IgA and mean postimmunization level was 5.0 micrograms/mg IgA. The adults' mean nasal preimmunization level was 0.98 microgram/mg IgA and mean postimmunization level was 3.0 micrograms/mg IgA. Salivary antibody responses generally followed the pattern of nasal antibody responses. These data suggest that parenteral administration with the Hib capsular polysaccharide can produce a mucosal antibody response. Furthermore, although serum antibody responses to PRP vaccination are greater in adults than in children, mucosal antibody responses are comparable. | lld:pubmed |
| pubmed-article:6605372 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6605372 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6605372 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6605372 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6605372 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6605372 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:6605372 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6605372 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6605372 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6605372 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:6605372 | pubmed:issn | 0091-6749 | lld:pubmed |
| pubmed-article:6605372 | pubmed:author | pubmed-author:InselR ARA | lld:pubmed |
| pubmed-article:6605372 | pubmed:author | pubmed-author:PichicheroM... | lld:pubmed |
| pubmed-article:6605372 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6605372 | pubmed:volume | 72 | lld:pubmed |
| pubmed-article:6605372 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6605372 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6605372 | pubmed:pagination | 481-6 | lld:pubmed |
| pubmed-article:6605372 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:meshHeading | pubmed-meshheading:6605372-... | lld:pubmed |
| pubmed-article:6605372 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6605372 | pubmed:articleTitle | Mucosal antibody response to parenteral vaccination with Haemophilus influenzae type b capsule. | lld:pubmed |
| pubmed-article:6605372 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6605372 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:6605372 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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