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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-12-21
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pubmed:abstractText |
The variability of the MHC restricted receptor on murine T cells was examined by comparing tryptic peptide fingerprints of the receptor isolated fom three T cell hybridomas and a T cell tumor. Both variable and constant peptides were seen. Constant peptides were most apparent when comparing receptors from the same mouse strain. Peptide fingerprints of receptors from two independent T cell hybridomas with the same idiotype and specificity were identical. We also describe a molecule detected on the surface of a human T cell leukemia whose properties were identical to those reported for the MHC receptor on normal human T cells. The molecule was a dimer of 85,000-90,000 MW containing a 46,000 MW acidic alpha-chain and an unrelated 40,000 MW neutral beta-chain.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0092-8674
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-302
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6605199-Animals,
pubmed-meshheading:6605199-Cell Line,
pubmed-meshheading:6605199-Humans,
pubmed-meshheading:6605199-Hybridomas,
pubmed-meshheading:6605199-Leukemia, Lymphoid,
pubmed-meshheading:6605199-Major Histocompatibility Complex,
pubmed-meshheading:6605199-Mice,
pubmed-meshheading:6605199-Mice, Inbred BALB C,
pubmed-meshheading:6605199-Molecular Weight,
pubmed-meshheading:6605199-Peptides,
pubmed-meshheading:6605199-Receptors, Antigen, T-Cell,
pubmed-meshheading:6605199-Species Specificity,
pubmed-meshheading:6605199-T-Lymphocytes,
pubmed-meshheading:6605199-Trypsin
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pubmed:year |
1983
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pubmed:articleTitle |
The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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