Linked Life Data

6604926

Source:http://linkedlifedata.com/resource/pubmed/id/6604926

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1983-11-23
pubmed:abstractText
A prototype instrument based on the coincidence detection of annihilation radiation was built to control the arterial concentration of a radionuclide as a uniformly increasing ramp function over a preset injection interval (ranging from 1.6 min to 13.6 h). The device was designed to accommodate radionuclides of different physical and biological half-life, and the physiological characteristics of the system being studied. A kinetic model based on the Kety-Schmidt integral was developed to permit the determination of cerebral blood flow (CBF). Both the kinetic model and the ramp injector were tested in cats studied with the PETT III positron emission tomograph and 4-(18F)-fluoroantipyrine as the CBF tracer. The ratio lambda/f of the brain-to-blood partition coefficient (lambda) and blood flow (f) were determined simultaneously by serial measurements with positron emission tomography.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0031-9155
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
963-72
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The ramp injection of radiotracers for blood flow measurement by emission tomography.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't