Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-6-10
pubmed:abstractText
Macrophages treated with culture fluids from EL-4 cells, a continuous T cell line, were activated to kill mKSA-TU-5 fibrosarcoma cells, amastigotes of Leishmania tropica, and schistosomula of Schistosoma mansoni. Active EL-4 factors eluted from Sephadex G-100 in two distinct regions: molecular weight 45,000 (activities induced killing of unrelated intracellular and extracellular targets) and molecular weight 23,000 (activities induced killing of extracellular targets only). These results confirm heterogeneity among activation signals for the induction of macrophage microbicidal and tumoricidal activities. Factors that induced cytocidal activity against extracellular tumor cells and schistosomula were distinct from those that induced destruction of intracellular amastigotes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-115917, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-13782523, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-330759, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-368287, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-376721, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-378423, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-632578, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-6773672, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-681749, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-7005333, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-7011574, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-712076, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-7159937, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-7217671, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-7299130, http://linkedlifedata.com/resource/pubmed/commentcorrection/6601625-7317951
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0019-9567
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
820-4
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Activation of macrophages for microbicidal and tumoricidal effector functions by soluble factors from EL-4, a continuous T cell line.
pubmed:publicationType
Journal Article