Linked Life Data

6601203

Source:http://linkedlifedata.com/resource/pubmed/id/6601203

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-5-5
pubmed:abstractText
The expression of tissue factor activity was evaluated in homogenates and in intact whole cells from a variety of human and nonhuman cell lines of normal and neoplastic origin. A high degree of species specificity in the interaction of tissue factor with other coagulation factors was observed in guinea pig, rat, mouse, and hamster cells. Tissue factor was present in significant amounts in homogenates of both the normal and neoplastic cells tested in all four species examined. No correlation was observed between the amount of tissue factor detected in cell homogenates and the derivation of the cell line from normal versus neoplastic tissue. Intact cells also expressed tissue factor activity, but lower levels were found in most cell lines examined. The significance of these data is discussed with regard to fibrin deposition around tumors in vivo.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0027-8874
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Tissue factor activity of normal and neoplastic cells: quantitation and species specificity.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't