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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-5-27
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pubmed:abstractText |
The mode of expression of novel HLA-DR antigens on hybrids of human T and B lymphoblastoid cell lines (LCL) was examined by several approaches. In each case, the results indicated that the novel antigens are T-LCL-encoded. First, hybrids of sublines of the T-LCL CEM with three different B-LCL express indistinguishable sets of novel HLA-DR antigens. Second, the novel HLA-DR and MT specificities of WI-L2 x HSB (a hybrid of a subline of the T-LCL HSB and the B-LCL WI-L2) match those of SB, a B-LCL derived from the same individual as HSB. Finally, an immunoselected variant of SB x CEM.1 (a hybrid of a subline of CEM and SB) lacking one copy of chromosome 6 and one of the hybrid's novel HLA-DR specificities also lacks a class I antigen known to be encoded by CEM.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0093-7711
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
411-25
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6601057-Antibodies, Monoclonal,
pubmed-meshheading:6601057-B-Lymphocytes,
pubmed-meshheading:6601057-Cell Line,
pubmed-meshheading:6601057-Histocompatibility Antigens Class II,
pubmed-meshheading:6601057-Humans,
pubmed-meshheading:6601057-Hybrid Cells,
pubmed-meshheading:6601057-Immune Sera,
pubmed-meshheading:6601057-T-Lymphocytes
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pubmed:year |
1983
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pubmed:articleTitle |
Expression of T-lymphoblast-encoded HLA-DR antigens on human T-B lymphoblast hybrids.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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