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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1983-1-27
|
| pubmed:abstractText |
Cells isolated from embryonic chick intestine in culture convert 25-hydroxyvitamin-D3 to a number of more polar metabolites. Two of these metabolites have been identified with chemical and chromatographic methods as 24,25-dihydroxyvitamin-D3 (24,25(OH)2D3) and 1,25-dihydroxyvitamin-D3 (1,25(OH)2D3). The enzymes conform to substrate saturation kinetics. The apparent Km for substrate for the synthesis of 1,25(OH)2D3 and 24,25(OH)2D3 is 70 nM and 29 nM, respectively.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0013-7227
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
112
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
378-80
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:6600165-24,25-Dihydroxyvitamin D 3,
pubmed-meshheading:6600165-Animals,
pubmed-meshheading:6600165-Calcitriol,
pubmed-meshheading:6600165-Cells, Cultured,
pubmed-meshheading:6600165-Chick Embryo,
pubmed-meshheading:6600165-Chromatography, High Pressure Liquid,
pubmed-meshheading:6600165-Dihydroxycholecalciferols,
pubmed-meshheading:6600165-Intestines,
pubmed-meshheading:6600165-Kinetics
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Cells isolated from embryonic intestine synthesize 1,25-dihydroxyvitamin-D3 and 24,25-dihydroxyvitamin-D3 in culture.
|
| pubmed:publicationType |
Journal Article
|