Linked Life Data

6595454

Source:http://linkedlifedata.com/resource/pubmed/id/6595454

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-2-6
pubmed:abstractText
A previous report from the Evans County, Ga., cohort correlated low base-line retinol levels in 1960-62 to an increased risk of cancer developing in the following 12-14 years. So that this inverse association could be retested, retinol determinations were performed on sera in 135 incident cancer cases, identified during a vital status follow-up in 1981, and in 237 controls matched by race, sex, age, and date of venipuncture. The serum was drawn during the second cohort examination between 1967 and 1969 and stored at -20 degrees C until analysis by high-pressure liquid chromatography in January 1982. Eligible for the study were patients whose initial cancer diagnosis was established more than 24 months after venipuncture. Base-line retinol levels of subsequent cancer cases and their matched controls were similar in the 4 race-sex groups. The risk of cancer at all sites associated with the lowest retinol quintile was similar to that associated with the highest quintile. In multivariate analysis, with control for age, cholesterol, body mass, smoking status, and social class, no significant relationship of serum retinol and case status was found. In summary, these data fail to confirm the strong dose-response relationship between baseline retinol levels and subsequent cancer reported in the previous study.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0027-8874
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1455-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Serum retinol and risk of subsequent cancer: extension of the Evans County, Georgia, study.
pubmed:publicationType
Journal Article