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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
51-52
|
pubmed:dateCreated |
1985-2-5
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pubmed:abstractText |
In 42 control subjects and 134 patients with benign or malignant disease of the pancreas or large intestine, the recently produced tumour-associated antigen CA 12-5 was determined together with CEA and CA 19-9. Only 4% of controls and patients with benign disease (except those with acute pancreatitis) had CA 12-5 values above 35 U/ml, compared with 60% of patients with pancreas carcinoma and 21% with colon carcinoma. For the former (pancreas carcinoma) there was also a good correlation to stage of tumour (0 of 6 tumours stage TxN0M0, 7 of 11 TxN1M0, 16 of 20 TxN1M1 greater than 35 U/ml) and progression of the malignancy. Simultaneous determination of all three antigens increased the rate of tumour-marker positive patients from 87% (CA 19-9) to 92% for pancreas carcinoma and from 25% (CEA) to 51% for colon carcinoma.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0012-0472
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
|
pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1949-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6595110-Acute Disease,
pubmed-meshheading:6595110-Adenocarcinoma,
pubmed-meshheading:6595110-Animals,
pubmed-meshheading:6595110-Antigens, Neoplasm,
pubmed-meshheading:6595110-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:6595110-Carcinoembryonic Antigen,
pubmed-meshheading:6595110-Colitis,
pubmed-meshheading:6595110-Colonic Neoplasms,
pubmed-meshheading:6595110-Digestive System Neoplasms,
pubmed-meshheading:6595110-Female,
pubmed-meshheading:6595110-Humans,
pubmed-meshheading:6595110-Male,
pubmed-meshheading:6595110-Mice,
pubmed-meshheading:6595110-Mice, Nude,
pubmed-meshheading:6595110-Neoplasm Staging,
pubmed-meshheading:6595110-Pancreatic Neoplasms,
pubmed-meshheading:6595110-Pancreatitis
|
pubmed:year |
1984
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pubmed:articleTitle |
[CA 12-5 in cancer of the digestive tract. A comparison with CA 19-9 and CEA in cancer of the pancreas and colon].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|